Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472293 | 0.97 | POLB (0.41) | DNM1KDM4ECYP1A2KMT2AMEN1 | |
| SCHEMBL8477309 | 0.94 | EGFR (0.42) | DNM1KDM4ECYP1A2KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8479377 | 0.89 | DNM1 (0.45) | DNM1KDM4ECYP1A2KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8473318 | 0.89 | MEN1 (0.38) | DNM1KDM4ECYP1A2KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8478096 | 0.88 | DNM1 (0.48) | DNM1KDM4ECYP1A2KMT2AMEN1 | |
| SCHEMBL8475687 | 0.88 | EGFR (0.48) | DNM1KDM4ECYP1A2KMT2AMEN1 | |
| SCHEMBL8472528 | 0.87 | KDM4E (0.49) | KDM4EKMT2AMEN1EGFRSRC | |
| SCHEMBL8477129 | 0.86 | KDM4E (0.43) | KDM4EKMT2AMEN1CNR2POLB | |
| Hydrochloric Acid SCHEMBL8472052 | 0.85 | KDM4E (0.42) | DNM1KDM4EEGFRSRCCNR2 | |
| SCHEMBL8476437 | 0.85 | KDM4E (0.39) | DNM1KDM4EEGFRSRCPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |