Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8473318 | 0.94 | MEN1 (0.38) | EGFRSRCKDM4EMAPTDNM1 | |
| SCHEMBL8472569 | 0.94 | DNM1 (0.43) | EGFRSRCKDM4EMAPTDNM1 | |
| SCHEMBL8475687 | 0.94 | EGFR (0.48) | EGFRSRCKDM4EMAPTDNM1 | |
| Hydrochloric Acid SCHEMBL8479377 | 0.93 | DNM1 (0.45) | EGFRSRCKDM4EDNM1ALDH1A1 | |
| SCHEMBL8472293 | 0.93 | POLB (0.41) | EGFRSRCKDM4EMAPTDNM1 | |
| Hydrochloric Acid SCHEMBL8478096 | 0.92 | DNM1 (0.48) | KDM4EDNM1MEN1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL8472052 | 0.91 | KDM4E (0.42) | EGFRSRCKDM4EMAPTDNM1 | |
| SCHEMBL8476437 | 0.91 | KDM4E (0.39) | EGFRSRCKDM4EMAPTDNM1 | |
| Hydrochloric Acid SCHEMBL8476884 | 0.91 | ALDH1A1 (0.42) | EGFRSRCKDM4EMAPTDNM1 | |
| SCHEMBL7615354 | 0.90 | DNM1 (0.41) | EGFRSRCKDM4EMAPTDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |