Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | MARK3 | P27448 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.33 |
| ▸ | NEK4 | P51957 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472573 | 0.83 | KMT2A (0.44) | KMT2AMEN1PTGER4PLA2G2APOLB | |
| SCHEMBL8476486 | 0.80 | PTGER4 (0.50) | KMT2AMEN1PTGER4SMN1; SMN2KDM4E | |
| SCHEMBL8476671 | 0.77 | KMT2A (0.47) | KMT2AMEN1PTGER4KDM4EALDH1A1 | |
| SCHEMBL8472027 | 0.75 | L3MBTL1 (0.47) | KMT2AMEN1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8476230 | 0.75 | PTGER4 (0.47) | KMT2APTGER4KDM4EALDH1A1POLB | |
| SCHEMBL8474553 | 0.75 | PTGER4 (0.47) | KMT2AMEN1PTGER4SMN1; SMN2KDM4E | |
| SCHEMBL8472402 | 0.75 | PTGER4 (0.49) | KMT2AMEN1PTGER4SMN1; SMN2KDM4E | |
| SCHEMBL8477130 | 0.75 | KMT2A (0.55) | KMT2AMEN1PTGER4KDM4EALDH1A1 | |
| SCHEMBL8472117 | 0.74 | L3MBTL1 (0.46) | KMT2AMEN1PTGER4SMN1; SMN2KDM4E | |
| SCHEMBL8476027 | 0.74 | KMT2A (0.52) | KMT2APTGER4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |