Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TSPO | P30536 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472402 | 0.92 | PTGER4 (0.49) | PTGER4KMT2AELANEMEN1POLB | |
| SCHEMBL8476486 | 0.92 | PTGER4 (0.50) | PTGER4KMT2AELANEMEN1POLB | |
| SCHEMBL8476230 | 0.90 | PTGER4 (0.47) | PTGER4KMT2AELANEPOLBRAD52 | |
| SCHEMBL8472303 | 0.86 | POLB (0.43) | PTGER4KMT2AMEN1TSPOPOLB | |
| SCHEMBL7609587 | 0.86 | KMT2A (0.46) | PTGER4KMT2AELANEMEN1POLB | |
| SCHEMBL8476671 | 0.86 | KMT2A (0.47) | PTGER4KMT2AMEN1POLBRAD52 | |
| SCHEMBL8477130 | 0.86 | KMT2A (0.55) | PTGER4KMT2AELANEMEN1KDM4E | |
| SCHEMBL8476027 | 0.85 | KMT2A (0.52) | PTGER4KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL8473259 | 0.84 | KMT2A (0.45) | PTGER4KMT2AMEN1LMNA | |
| SCHEMBL8475477 | 0.84 | KDM4E (0.39) | PTGER4POLBKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |