Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | MTTP | P55157 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | KLRK1 | P26718 | 2/20 | 0.37 |
| ▸ | MICA | Q29983 | 2/20 | 0.37 |
| ▸ | RAET1L | Q5VY80 | 2/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474108 | 0.85 | MEN1 (0.45) | ALDH1A1KDM4ENPSR1LMNAMEN1 | |
| SCHEMBL8472074 | 0.84 | CHRNB2 (0.45) | ALDH1A1ESR1ESR2MTTPHPGD | |
| SCHEMBL8471802 | 0.84 | ESR1 (0.49) | ALDH1A1KDM4ENPSR1LMNAKMT2A | |
| SCHEMBL8473577 | 0.83 | HPGD (0.42) | ALDH1A1KDM4ENPSR1LMNAMAPT | |
| SCHEMBL8470206 | 0.83 | PDE4B (0.42) | ALDH1A1KDM4ENPSR1LMNAMEN1 | |
| SCHEMBL8582518 | 0.82 | ESR1 (0.44) | ALDH1A1KDM4ENPSR1LMNAMEN1 | |
| SCHEMBL8471797 | 0.82 | ESR1 (0.43) | ALDH1A1KDM4ENPSR1LMNAMEN1 | |
| SCHEMBL8473453 | 0.81 | ALDH1A1 (0.41) | ALDH1A1LMNAKMT2AESR1ESR2 | |
| SCHEMBL8474716 | 0.81 | ABCB1 (0.47) | KMT2AESR1ESR2LIPEMTTP | |
| SCHEMBL8471317 | 0.81 | ALDH1A1 (0.48) | ALDH1A1KDM4ENPSR1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919795-A | ATHEROSCLEROSIS THERAPY | PFIZER INC. (US) | 1999-07-06 | — | — | US | disclosed |