Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | MTTP | P55157 | 5/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8470206 | 0.89 | PDE4B (0.42) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL8471802 | 0.86 | ESR1 (0.49) | KMT2AKDM4EALDH1A1LMNANPSR1 | |
| SCHEMBL8472683 | 0.85 | MTTP (0.42) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL8473047 | 0.85 | ALDH1A1 (0.43) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL8582518 | 0.83 | ESR1 (0.44) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL8582957 | 0.83 | ESR1 (0.44) | KDM4EALDH1A1LMNANPSR1ESR1 | |
| SCHEMBL8472958 | 0.83 | SMO (0.43) | KDM4ELMNAESR1ESR2LIPE | |
| SCHEMBL8471797 | 0.83 | ESR1 (0.43) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL8470752 | 0.83 | ESR1 (0.43) | KDM4EALDH1A1LMNANPSR1ESR1 | |
| SCHEMBL8473577 | 0.83 | HPGD (0.42) | KDM4EALDH1A1LMNANPSR1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919795-A | ATHEROSCLEROSIS THERAPY | PFIZER INC. (US) | 1999-07-06 | — | — | US | disclosed |