Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.49 |
| ▸ | REN | P00797 | 4/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.44 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.43 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1350878 | 0.92 | PTPN1 (0.57) | BCL2PTPN1PPARGPPARACTSS | |
| SCHEMBL1350409 | 0.92 | PTPN1 (0.57) | BCL2PTPN1PPARGPPARACTSS | |
| SCHEMBL19190003 | 0.89 | BCL2 (0.52) | BCL2PTPN1RENPPARACTSS | |
| SCHEMBL792956 | 0.86 | BCL2 (0.64) | BCL2PTPN1RENPPARGPPARA | |
| SCHEMBL8523666 | 0.85 | CTSS (0.52) | BCL2PTPN1CTSSCTSLCTSB | |
| SCHEMBL13571256 | 0.85 | PTPN1 (0.51) | BCL2PTPN1RENPPARGPPARA | |
| SCHEMBL13571255 | 0.85 | PTPN1 (0.51) | BCL2PTPN1RENPPARGPPARA | |
| SCHEMBL13639719 | 0.84 | BCL2 (0.47) | BCL2PTPN1RENPPARGPPARA | |
| SCHEMBL19190694 | 0.84 | HDAC8 (0.56) | BCL2PTPN1RENCTSSCTSL | |
| SCHEMBL8552202 | 0.82 | BCL2 (0.48) | BCL2CTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999004792-A1 | NOVEL AZATYROSINE ANALOGUES AND PROCESS OF PREPARATION THEREOF | TSAI, HANSEN (TW) | 1999-02-04 | — | — | WO | disclosed |