Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.57 |
| ▸ | PPARA | Q07869 | 3/20 | 0.54 |
| ▸ | ACE | P12821 | 2/20 | 0.53 |
| ▸ | BCL2 | P10415 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.51 |
| ▸ | PPARG | P37231 | 4/20 | 0.50 |
| ▸ | YAP1 | P46937 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1350878 | 1.00 | PTPN1 (0.57) | PTPN1PPARAACEBCL2ITGB3 | |
| SCHEMBL8474091 | 0.92 | BCL2 (0.50) | PTPN1PPARAACEBCL2PPARG | |
| SCHEMBL13571255 | 0.91 | PTPN1 (0.51) | PTPN1PPARAACEBCL2ITGB3 | |
| SCHEMBL13571256 | 0.91 | PTPN1 (0.51) | PTPN1PPARAACEBCL2ITGB3 | |
| SCHEMBL19190003 | 0.89 | BCL2 (0.52) | PTPN1PPARABCL2CTSSCTSL | |
| SCHEMBL8523666 | 0.87 | CTSS (0.52) | PTPN1BCL2CTSSCTSLCTSB | |
| SCHEMBL13639719 | 0.86 | BCL2 (0.47) | PTPN1PPARAACEBCL2PPARG | |
| SCHEMBL19190694 | 0.86 | HDAC8 (0.56) | PTPN1BCL2CTSSCTSLCTSB | |
| SCHEMBL6914964 | 0.85 | ITGB3 (0.53) | PTPN1PPARAACEITGB3ITGA2B | |
| SCHEMBL193473 | 0.85 | PTPN1 (0.73) | PTPN1PPARAACEBCL2ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2388247-B1 | Histone deacetylase inhibitors | UNIV TAIPEI MEDICAL (TW) | 2017-08-02 | — | — | EP | disclosed |
| EP-2388247-B1 | Histone deacetylase inhibitors | UNIV TAIPEI MEDICAL (TW) | 2017-08-02 | — | — | EP | disclosed |
| US-8242282-B2 | Histone deacetylase inhibitors | TAIPEI MEDICAL UNIVERSITY (TW) | 2012-08-14 | — | — | US | disclosed |
| CN-102267923-A | Histone deacetylase inhibitors | — | 2011-12-07 | — | — | CN | disclosed |
| US-20110288133-A1 | HISTONE DEACETYLASE INHIBITORS | TAIPEI MEDICAL UNIVERSITY (TW) | 2011-11-24 | — | — | US | disclosed |
| EP-2388247-A2 | Histone deacetylase inhibitors | Taipei Medical University (TW) | 2011-11-23 | — | — | EP | disclosed |
| US-8039296-B2 | Organic thin film transistor array panel and manufacturing method thereof | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2011-10-18 | — | — | US | disclosed |
| US-5869507-A | Azatyrosine analogues | Wang, Hui-Po (TW) | 1999-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288133-A1 | HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC5, HDAC2 | PTPN1 4407/4885PPARA 2332/4885ACE 2594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.