Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.52 |
| ▸ | CTSK | P43235 | 8/20 | 0.52 |
| ▸ | CTSB | P07858 | 3/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.51 |
| ▸ | BCL2 | P10415 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 5/20 | 0.48 |
| ▸ | PSMB9 | P28065 | 4/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.48 |
| ▸ | PSMB10 | P40306 | 4/20 | 0.47 |
| ▸ | PSMB2 | P49721 | 4/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1350878 | 0.87 | PTPN1 (0.57) | CTSSCTSKCTSBCTSLBCL2 | |
| SCHEMBL1350409 | 0.87 | PTPN1 (0.57) | CTSSCTSKCTSBCTSLBCL2 | |
| SCHEMBL19190003 | 0.87 | BCL2 (0.52) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL1353726 | 0.86 | PSMB1 (0.54) | CTSSCTSKCTSBCTSLBCL2 | |
| SCHEMBL8474091 | 0.85 | BCL2 (0.50) | CTSSCTSKCTSBCTSLBCL2 | |
| SCHEMBL1349202 | 0.84 | PSMB1 (0.53) | CTSSCTSKCTSBCTSLBCL2 | |
| SCHEMBL19190694 | 0.84 | HDAC8 (0.56) | CTSSCTSKCTSBCTSLBCL2 | |
| SCHEMBL1349239 | 0.84 | PSMB1 (0.51) | CTSSCTSKCTSBCTSLBCL2 | |
| SCHEMBL19190193 | 0.84 | PSMB1 (0.51) | CTSSCTSKCTSBCTSLBCL2 | |
| SCHEMBL8552202 | 0.82 | BCL2 (0.48) | CTSSCTSKCTSBCTSLBCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869507-A | Azatyrosine analogues | Wang, Hui-Po (TW) | 1999-02-09 | — | — | US | disclosed |
| WO-1999004792-A1 | NOVEL AZATYROSINE ANALOGUES AND PROCESS OF PREPARATION THEREOF | TSAI, HANSEN (TW) | 1999-02-04 | — | — | WO | disclosed |