Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 9/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MOGAT2 | Q3SYC2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474108 | 0.85 | MEN1 (0.45) | MTTPCA1CA2CA7CA9 | |
| SCHEMBL8472074 | 0.81 | CHRNB2 (0.45) | MTTPHPGDESR1ESR2ALDH1A1 | |
| SCHEMBL8473518 | 0.81 | MTTP (0.40) | MTTPLMNAESR1ESR2KDM4E | |
| SCHEMBL8471802 | 0.81 | ESR1 (0.49) | MTTPKMT2ALMNAHPGDESR1 | |
| SCHEMBL8470752 | 0.81 | ESR1 (0.43) | MTTPLMNAESR1ESR2KDM4E | |
| SCHEMBL8474040 | 0.80 | MTTP (0.37) | MTTPLMNAESR1ESR2KDM4E | |
| SCHEMBL8474716 | 0.80 | ABCB1 (0.47) | MTTPKMT2AMOGAT2ESR1ESR2 | |
| SCHEMBL8582518 | 0.80 | ESR1 (0.44) | MTTPKMT2AMEN1LMNAESR1 | |
| SCHEMBL8470841 | 0.79 | EPHX2 (0.40) | MTTPKMT2AMAPTHPGDKDM4E | |
| SCHEMBL8473047 | 0.79 | ALDH1A1 (0.43) | MTTPKMT2AMEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919795-A | ATHEROSCLEROSIS THERAPY | PFIZER INC. (US) | 1999-07-06 | — | — | US | disclosed |