Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HEXA | P06865 | 1/20 | 0.42 |
| ▸ | HEXB | P07686 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8478757 | 0.88 | MAPT (0.44) | POLBGAAHEXAHEXBPTGS2 | |
| SCHEMBL8474655 | 0.84 | HEXA (0.42) | POLBGAAHEXAHEXBPTGS2 | |
| SCHEMBL8476303 | 0.83 | HEXA (0.39) | HEXAHEXBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8480173 | 0.80 | PTGS2 (0.44) | POLBGAAPTGS2ESR2CYP1A2 | |
| SCHEMBL8583542 | 0.80 | KDM4E (0.41) | GAAPTGS2NPC1HPGDRAB9A | |
| SCHEMBL8474614 | 0.75 | HEXA (0.46) | POLBGAAHEXAHEXBPTGS2 | |
| SCHEMBL8475225 | 0.73 | MAPT (0.44) | POLBGAAHEXAHEXBPTGS2 | |
| SCHEMBL8474965 | 0.71 | ALDH1A1 (0.37) | GAAHEXAHEXBL3MBTL1NPC1 | |
| SCHEMBL8474322 | 0.70 | MAPT (0.37) | GAAHEXAHEXBPTGS2CYP1A2 | |
| SCHEMBL8481099 | 0.69 | HEXA (0.39) | POLBGAAHEXAHEXBPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |