Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | HEXA | P06865 | 1/20 | 0.38 |
| ▸ | HEXB | P07686 | 1/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.36 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474672 | 0.88 | NPC1 (0.34) | MAPTHEXAHEXBGAAKDM4E | |
| SCHEMBL8474655 | 0.88 | HEXA (0.42) | MAPTCASP3SENP8SENP7SENP6 | |
| SCHEMBL8478542 | 0.87 | PTGS2 (0.47) | MAPTHEXAHEXBCDK1PTGS2 | |
| SCHEMBL8477183 | 0.87 | MAPT (0.36) | MAPTGAAKDM4ENPC1RAB9A | |
| SCHEMBL8478757 | 0.85 | MAPT (0.44) | MAPTCASP3SENP8SENP7SENP6 | |
| SCHEMBL8474614 | 0.84 | HEXA (0.46) | MAPTCASP3SENP8SENP7SENP6 | |
| SCHEMBL8478355 | 0.76 | PTGS2 (0.42) | MAPTPTGS2ESR2POLBGAA | |
| SCHEMBL8474322 | 0.74 | MAPT (0.37) | MAPTHEXAHEXBPTGS2GAA | |
| SCHEMBL8480049 | 0.73 | PDE4B (0.36) | MAPTPTGS2POLBGAANPC1 | |
| SCHEMBL8474308 | 0.73 | POLB (0.43) | HEXAHEXBPTGS2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |