Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15267777 | 0.91 | SIGMAR1 (0.39) | TSHRSLC1A1GLAKMT2AMEN1 | |
| SCHEMBL12358676 | 0.91 | SIGMAR1 (0.39) | TSHRSLC1A1GLAKMT2AMEN1 | |
| SCHEMBL10012740 | 0.89 | SIGMAR1 (0.40) | TSHRSLC1A1GLASMN1; SMN2KMT2A | |
| SCHEMBL22927604 | 0.81 | NOTUM (0.38) | KMT2AMEN1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21706214 | 0.81 | NOTUM (0.38) | KMT2AMEN1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17706710 | 0.81 | L3MBTL1 (0.43) | TSHRGLASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11567612 | 0.81 | L3MBTL1 (0.43) | TSHRGLASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL17766650 | 0.79 | MAPT (0.39) | TSHRSMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL29589915 | 0.78 | SIGMAR1 (0.36) | KMT2AMEN1MAPT | |
| SCHEMBL30842354 | 0.77 | MEN1 (0.41) | TSHRSMN1; SMN2KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919432-A | Polyaminated ligands and metal complexes thereof | GUERBET S.A. (FR) | 1999-07-06 | — | — | US | disclosed |
| US-5712389-A | Polyaminated ligands and metal complexes thereof | GUERBET S.A. (FR) | 1998-01-27 | — | — | US | disclosed |
| EP-0661279-A1 | Polyaminated ligands, metal complexes, process for their preparation and diagnostic and therapeutic applications | GUERBET S.A. (FR) | 1995-07-05 | — | — | EP | disclosed |