Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | HTR1A | P08908 | 4/20 | 0.44 |
| ▸ | HTR2A | P28223 | 4/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1545312 | 0.80 | HTR1D (0.50) | DRD2HTR1AHTR2AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL1545002 | 0.80 | HTR1D (0.49) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL8854146 | 0.79 | HTR1A (0.61) | DRD2HTR1AHTR2A | |
| SCHEMBL9377355 | 0.78 | HTR1A (0.65) | DRD2HTR1AHTR2AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL9381340 | 0.76 | HTR1A (0.62) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL9117307 | 0.74 | HTR1D (0.50) | DRD2HTR1AHTR2A | |
| SCHEMBL8787809 | 0.72 | HTR1A (0.41) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL6220554 | 0.72 | HTR1A (0.40) | HTR1A | |
| SCHEMBL8858982 | 0.71 | HTR2A (0.57) | DRD2HTR1AHTR2AHTR6DRD3 | |
| SCHEMBL1545386 | 0.71 | HTR1D (0.47) | DRD2HTR1AHTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6001834-A | PSYCHOLOGICAL DISORDERS, ANALGESICS | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1999-12-14 | — | — | US | disclosed |
| US-5965546-A | ANTIPSYCHOTIC AND ANALGESIC AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1999-10-12 | — | — | US | disclosed |