Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8789213 | 0.94 | DRD2 (0.43) | HTR1AHTR2ADRD2HTR7HTR6 | |
| SCHEMBL1545312 | 0.82 | HTR1D (0.50) | HTR1AHTR2ADRD2HTR7HTR6 | |
| SCHEMBL9376457 | 0.81 | HTR1A (0.56) | HTR1AHTR2ADRD2HTR7HTR6 | |
| Hydrochloric Acid SCHEMBL1545002 | 0.81 | HTR1D (0.49) | HTR1AHTR2ADRD2HTR7HTR6 | |
| SCHEMBL8787429 | 0.80 | DRD2 (0.47) | HTR1AHTR2ADRD2ACHE | |
| Hydrochloric Acid SCHEMBL8787530 | 0.79 | DRD2 (0.46) | HTR1AHTR2ADRD2ACHE | |
| SCHEMBL8788375 | 0.76 | DRD2 (0.40) | HTR2ADRD2HTR7ACHE | |
| SCHEMBL1544931 | 0.76 | ACHE (0.71) | HTR1AHTR2ADRD2ACHE | |
| SCHEMBL9117307 | 0.76 | HTR1D (0.50) | HTR1AHTR2ADRD2ACHE | |
| SCHEMBL1545242 | 0.76 | HTR1A (0.45) | HTR1AHTR2ADRD2HTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730452-A4 | HETEROARYLPIPERIDINES, PYRROLIDINES AND PIPERAZINES AND THEIR USE AS ANTIPSYCHOTICS AND ANALGETICS | HOECHST ROUSSEL PHARMA (US) | 1997-03-19 | — | — | EP | disclosed |
| EP-0730452-A1 | HETEROARYLPIPERIDINES, PYRROLIDINES AND PIPERAZINES AND THEIR USE AS ANTIPSYCHOTICS AND ANALGETICS | HOECHST MARION ROUSSEL, Inc. (US) | 1996-09-11 | — | — | EP | disclosed |