Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7809023 | 0.89 | ALOX5 (0.64) | ALOX5 | |
| SCHEMBL9009080 | 0.73 | ALOX5 (0.66) | ALOX5 | |
| SCHEMBL9302774 | 0.72 | ALOX5 (0.62) | ALOX5 | |
| SCHEMBL2685255 | 0.71 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL30108090 | 0.71 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9008940 | 0.71 | ALOX5 (0.63) | ALOX5 | |
| SCHEMBL9009119 | 0.71 | ALOX5 (0.63) | ALOX5 | |
| SCHEMBL2685256 | 0.69 | ALOX5 (0.66) | ALOX5 | |
| SCHEMBL9301767 | 0.67 | ALOX5 (0.59) | ALOX5 | |
| SCHEMBL9300351 | 0.67 | ALOX5 (0.61) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229034-B1 | Nicotinamide derivatives and their mimetics as inhibitors of PDE4 isozymes | PFIZER PROD INC (US) | 2005-04-13 | — | — | EP | disclosed |