Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2452569 | 0.85 | MAPT (0.42) | MAPTHTR2AHRH1DNM1ALDH1A1 | |
| SCHEMBL17261304 | 0.85 | HIF1A (0.38) | MAPTHTR2AHRH1DNM1HIF1A | |
| SCHEMBL27317562 | 0.81 | — | — | |
| SCHEMBL8476530 | 0.80 | L3MBTL1 (0.42) | MAPTHTR2AHRH1LMNATSHR | |
| SCHEMBL8474657 | 0.80 | CA12 (0.32) | MAPTHTR2AHRH1CA12CA2 | |
| SCHEMBL18050404 | 0.80 | DNM1 (0.35) | MAPTDNM1HIF1ALMNASMN1; SMN2 | |
| SCHEMBL17261305 | 0.80 | L3MBTL1 (0.36) | MAPTDNM1HIF1ALMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27482491 | 0.79 | CA1 (0.36) | MAPTHTR2AHRH1LMNAALDH1A1 | |
| SCHEMBL8474662 | 0.79 | MAPT (0.46) | MAPTLMNASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL8476531 | 0.79 | KDM4E (0.47) | MAPTCA12CA2CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120129240-A1 | BUFFER COMPOUNDS | SACHEM, INC. | 2012-05-24 | — | — | US | disclosed |