Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476530 | 0.82 | L3MBTL1 (0.42) | MAPTHTR2AHRH1L3MBTL1 | |
| SCHEMBL18159896 | 0.81 | LMNA (0.30) | L3MBTL1 | |
| SCHEMBL8475008 | 0.80 | MAPT (0.36) | CA12CA2CA3CA4CA6 | |
| SCHEMBL8476531 | 0.80 | KDM4E (0.47) | CA12CA2CA3CA4CA6 | |
| SCHEMBL15509645 | 0.80 | KDM4E (0.35) | KDM4EL3MBTL1 | |
| SCHEMBL11289109 | 0.79 | THRB (0.42) | KDM4EL3MBTL1 | |
| SCHEMBL19044278 | 0.77 | — | — | |
| SCHEMBL2452569 | 0.77 | MAPT (0.42) | CA12CA2CA3CA4CA6 | |
| SCHEMBL7582522 | 0.76 | — | — | |
| SCHEMBL4712809 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012071102-A2 | BUFFER COMPOUNDS | SACHEM, INC. (US) | 2012-05-31 | — | — | WO | disclosed |
| US-20120129240-A1 | BUFFER COMPOUNDS | SACHEM, INC. | 2012-05-24 | — | — | US | disclosed |