Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 17/20 | 0.57 |
| ▸ | CA9 | Q16790 | 15/20 | 0.57 |
| ▸ | CA1 | P00915 | 15/20 | 0.57 |
| ▸ | CA12 | O43570 | 4/20 | 0.57 |
| ▸ | CA3 | P07451 | 2/20 | 0.48 |
| ▸ | CA6 | P23280 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25762191 | 0.79 | RXRA (0.38) | CA2CA9CA1 | |
| SCHEMBL8481494 | 0.78 | CA2 (0.57) | CA2CA9CA1CA12CA3 | |
| SCHEMBL2005577 | 0.77 | CA2 (0.56) | CA2CA9CA1CA12CA3 | |
| SCHEMBL1926937 | 0.76 | CA2 (0.67) | CA2CA9CA1CA12CA3 | |
| SCHEMBL19474971 | 0.75 | CA2 (0.49) | CA2CA9CA1CA12CA3 | |
| SCHEMBL30406022 | 0.75 | CA2 (0.49) | CA2CA9CA1CA12CA3 | |
| SCHEMBL24444327 | 0.75 | ALDH1A1 (0.53) | MAOA | |
| SCHEMBL1830671 | 0.75 | RXRA (0.54) | MAOA | |
| SCHEMBL2837502 | 0.75 | ALDH1A1 (0.53) | MAOA | |
| SCHEMBL6171121 | 0.74 | CA2 (0.75) | CA2CA9CA1CA12CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859257-A | ANTIINFLAMMATORY, ANTIARTHRITIC AGENTS | G. D. SEARLE & CO. (US) | 1999-01-12 | — | — | US | disclosed |