Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4575028 | 0.74 | ALDH1A1 (0.41) | GAASMN1; SMN2GRIN1GRIN2ALMNA | |
| SCHEMBL17446141 | 0.73 | GSK3A (0.45) | ALDH1A1OPRL1POLBGSK3AGSK3B | |
| SCHEMBL13241898 | 0.71 | GAA (0.41) | TSHRGAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL4309714 | 0.68 | ELANE (0.42) | TSHRGAALMNAHSD11B1ALDH1A1 | |
| SCHEMBL4329563 | 0.67 | CHRM2 (0.36) | GAALMNAOPRL1GSK3AGSK3B | |
| SCHEMBL8475167 | 0.67 | GAA (0.36) | TSHRGAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8475165 | 0.67 | GAA (0.36) | TSHRGAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL4309775 | 0.65 | SMN1; SMN2 (0.37) | GAASMN1; SMN2OPRL1 | |
| SCHEMBL9257560 | 0.63 | TP53 (0.48) | MAPTLMNAALDH1A1POLB | |
| SCHEMBL6902727 | 0.62 | IDH1 (0.44) | GAALMNAHSD11B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939554-A | Diarylaminopropanediol and diarylmethyl-oxazolidinone compounds | NDSU RESEARCH FOUNDATION (US) | 1999-08-17 | — | — | US | disclosed |
| US-5623087-A | Method for preparation of optically active diarylalanines | NDSU-RESEARCH FOUNDATION (US) | 1997-04-22 | — | — | US | disclosed |