Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 10/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8475165 | 1.00 | GAA (0.36) | GAAMAPTRAB9ASMN1; SMN2IDH1 | |
| SCHEMBL8475478 | 0.73 | IDH1 (0.51) | IDH1HSD11B1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL8475475 | 0.73 | IDH1 (0.51) | IDH1HSD11B1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL15690233 | 0.72 | EGLN1 (0.34) | IDH1KDM4EPKMLMNAALDH1A1 | |
| SCHEMBL15690232 | 0.72 | IDH1 (0.34) | GAAMAPTRAB9ASMN1; SMN2IDH1 | |
| SCHEMBL20340441 | 0.67 | IDH1 (0.46) | GAAMAPTSMN1; SMN2IDH1HSD11B1 | |
| SCHEMBL8475159 | 0.67 | TSHR (0.36) | GAAMAPTRAB9ASMN1; SMN2HSD11B1 | |
| SCHEMBL7812799 | 0.67 | ALDH1A1 (0.35) | RAB9AIDH1HSD11B1ALDH1A1CYP1A2 | |
| SCHEMBL8520432 | 0.66 | OPRL1 (0.37) | GAAMAPTRAB9ASMN1; SMN2HSD11B1 | |
| Sulfuric Acid SCHEMBL9452309 | 0.65 | OPRM1 (0.37) | SMN1; SMN2HSD11B1TSHRALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939554-A | Diarylaminopropanediol and diarylmethyl-oxazolidinone compounds | NDSU RESEARCH FOUNDATION (US) | 1999-08-17 | — | — | US | disclosed |
| US-5623087-A | Method for preparation of optically active diarylalanines | NDSU-RESEARCH FOUNDATION (US) | 1997-04-22 | — | — | US | disclosed |