Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13204618 | 0.92 | CTSS (0.62) | CTSSCD74 | |
| SCHEMBL2977245 | 0.91 | CTSS (0.63) | CTSSCD74 | |
| SCHEMBL13687516 | 0.83 | CTSS (0.72) | CTSSCD74 | |
| SCHEMBL14015780 | 0.82 | CTSS (0.83) | CTSSCD74 | |
| SCHEMBL4712464 | 0.77 | CTSS (0.67) | CTSSCD74 | |
| SCHEMBL2983694 | 0.76 | CTSS (0.83) | CTSS | |
| SCHEMBL13687543 | 0.76 | CTSS (0.55) | CTSSCD74 | |
| SCHEMBL2978580 | 0.76 | CTSS (0.82) | CTSSCD74 | |
| SCHEMBL2981279 | 0.75 | CTSS (1.00) | CTSSCD74 | |
| SCHEMBL8408387 | 0.75 | CTSS (0.76) | CTSSCD74 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7429591-B2 | Substituted pyrazoles | ORTHO MCNEIL PHARMACEUTICAL, INC. (US) | 2008-09-30 | — | — | US | disclosed |
| US-7332494-B2 | Method for treating allergies using substituted pyrazoles | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-02-19 | — | — | US | disclosed |
| US-20030069240-A1 | Method for treating allergies using substituted pyrazoles | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069240-A1 | Method for treating allergies using substituted pyrazoles | TSLP, IL33, HRH2 | CTSS 294/4885CD74 519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.