Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472678 | 0.92 | RAB9A (0.40) | ALDH1A1KDM4ELMNATSHRHTT | |
| SCHEMBL8475916 | 0.89 | ALDH1A1 (0.49) | ALDH1A1KDM4ELMNATSHRHTT | |
| SCHEMBL8583082 | 0.88 | ALDH1A1 (0.48) | ALDH1A1KDM4ELMNATSHRHTT | |
| SCHEMBL8472329 | 0.88 | EGFR (0.41) | ALDH1A1KDM4EMAPTTP53KMT2A | |
| SCHEMBL8475833 | 0.88 | KDM4E (0.42) | ALDH1A1KDM4ELMNATSHRHTT | |
| SCHEMBL7616866 | 0.86 | PTGER4 (0.38) | ALDH1A1KDM4ESMN1; SMN2MAPTKMT2A | |
| SCHEMBL8472316 | 0.85 | RXFP1 (0.42) | ALDH1A1KDM4ELMNATSHRSMN1; SMN2 | |
| SCHEMBL8474409 | 0.84 | NPY5R (0.42) | ALDH1A1KDM4ELMNATSHRHTT | |
| SCHEMBL7612724 | 0.83 | ALDH1A1 (0.39) | ALDH1A1KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL8477343 | 0.82 | KDM4E (0.41) | ALDH1A1KDM4ELMNATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782988-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |