Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8583082 | 0.94 | ALDH1A1 (0.48) | ALDH1A1KDM4ELMNATSHRPKM | |
| SCHEMBL8472328 | 0.91 | KCNA5 (0.40) | ALDH1A1KDM4ELMNATSHRPKM | |
| SCHEMBL8475172 | 0.89 | ALDH1A1 (0.42) | ALDH1A1KDM4ELMNATSHRPKM | |
| SCHEMBL8472191 | 0.85 | TAS1R3 (0.39) | ALDH1A1KDM4ELMNATSHRPKM | |
| SCHEMBL8475687 | 0.84 | EGFR (0.48) | ALDH1A1KDM4ELMNATSHRHTT | |
| Hydrochloric Acid SCHEMBL8476884 | 0.83 | ALDH1A1 (0.42) | ALDH1A1KDM4ETSHRHTTMAPT | |
| SCHEMBL8475467 | 0.83 | PYGM (0.49) | ALDH1A1KDM4ELMNATSHRPKM | |
| SCHEMBL8477309 | 0.82 | EGFR (0.42) | ALDH1A1KDM4ETSHRHTTMAPT | |
| Hydrochloric Acid SCHEMBL8475186 | 0.82 | ALDH1A1 (0.41) | ALDH1A1KDM4ETSHRHTTSMN1; SMN2 | |
| SCHEMBL8476051 | 0.81 | RXFP1 (0.48) | ALDH1A1KDM4ELMNATSHRPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |