Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474991 | 0.86 | PTGS2 (0.38) | PTGS2LMNACA12CA1CA2 | |
| SCHEMBL6816552 | 0.86 | PTGS2 (0.40) | PTGS2LMNACA12CA1CA2 | |
| SCHEMBL8481099 | 0.80 | HEXA (0.39) | PTGS2LMNACA12CA1CA2 | |
| SCHEMBL8477582 | 0.78 | MAPT (0.38) | PTGS2LMNAESR2MAPT | |
| SCHEMBL8478177 | 0.77 | PTGS2 (0.39) | PTGS2LMNACA12CA1CA2 | |
| SCHEMBL8481612 | 0.77 | MAPT (0.35) | PTGS2LMNAACHEALDH1A1MAPT | |
| SCHEMBL8480091 | 0.77 | PTGS2 (0.47) | PTGS2LMNAESR2NPC1RAB9A | |
| SCHEMBL8476656 | 0.75 | ACHE (0.43) | PTGS2LMNACA1CA2ACHE | |
| SCHEMBL8480669 | 0.74 | HEXA (0.38) | PTGS2LMNAACHEESR2APP | |
| SCHEMBL8477185 | 0.73 | KDM4E (0.38) | PTGS2LMNAACHEALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |