Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 1/20 | 0.38 |
| ▸ | HEXB | P07686 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474810 | 0.89 | MAPT (0.37) | HEXAHEXBESR2ESR1POLB | |
| SCHEMBL8481099 | 0.88 | HEXA (0.39) | HEXAHEXBESR2ESR1POLB | |
| SCHEMBL8475695 | 0.87 | PDE4B (0.40) | GAAPTGS2LMNAGRIK2L3MBTL1 | |
| SCHEMBL8474991 | 0.81 | PTGS2 (0.38) | ESR2POLBGAAAPPPTGS2 | |
| SCHEMBL8479986 | 0.81 | PDE4A (0.41) | HEXAHEXBESR2ESR1GAA | |
| SCHEMBL8477582 | 0.79 | MAPT (0.38) | HEXAHEXBESR2ESR1POLB | |
| SCHEMBL8479901 | 0.78 | — | — | |
| SCHEMBL8474318 | 0.78 | ESR2 (0.41) | HEXAHEXBESR2ESR1POLB | |
| SCHEMBL8480653 | 0.78 | SLC10A2 (0.39) | PTGS2 | |
| SCHEMBL8474773 | 0.77 | MAPT (0.38) | HEXAHEXBESR2ESR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |