Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 6/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919161 | 0.82 | SLC18A3 (0.62) | SLC18A3ACHEGRM5EPHX1L3MBTL3 | |
| SCHEMBL3662252 | 0.80 | ACHE (0.63) | ACHEGRM5EPHX1L3MBTL3L3MBTL1 | |
| SCHEMBL8476630 | 0.78 | SLC18A3 (0.58) | SLC18A3ACHEGRM5EPHX1L3MBTL3 | |
| SCHEMBL5871923 | 0.77 | ACHE (0.62) | SLC18A3ACHEGRM5EPHX1L3MBTL3 | |
| SCHEMBL12442621 | 0.77 | ACHE (0.62) | SLC18A3ACHEGRM5EPHX1L3MBTL3 | |
| SCHEMBL2720515 | 0.77 | ACHE (0.62) | SLC18A3ACHEGRM5EPHX1L3MBTL3 | |
| SCHEMBL8472183 | 0.75 | SLC18A3 (0.55) | SLC18A3ACHEGRM5EPHX1L3MBTL3 | |
| SCHEMBL16695294 | 0.75 | ACHE (0.60) | ACHEEPHX1L3MBTL3L3MBTL1MGLL | |
| SCHEMBL8474593 | 0.74 | SLC18A3 (0.54) | SLC18A3ACHEGRM5EPHX1L3MBTL3 | |
| SCHEMBL1719734 | 0.74 | MGLL (0.68) | SLC18A3ACHEMGLLHSD11B1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919797-A | DIAGNOSIS, THERAPY PSYCHOLOGICAL DISORDERS | EMORY UNIVERSITY (US) | 1999-07-06 | — | — | US | disclosed |
| WO-1997040010-A1 | HALOGENATED NAPHTHYL METHOXY PIPERIDINES FOR MAPPING SEROTONIN TRANSPORTER SITES | EMORY UNIVERSITY (US) | 1997-10-30 | — | — | WO | disclosed |