Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1487258 | 0.85 | ALDH1A1 (0.59) | ALDH1A1LMNAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL8471876 | 0.84 | ALDH1A1 (0.41) | ALDH1A1LMNAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL8472856 | 0.83 | POLB (0.48) | ALDH1A1LMNAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL8066284 | 0.81 | ALDH1A1 (0.45) | ALDH1A1HTTCA1CA2TSHR | |
| SCHEMBL8067867 | 0.77 | POLB (0.49) | ALDH1A1LMNAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL8066264 | 0.77 | MAPK1 (0.47) | ALDH1A1LMNAHTTKMT2ACA1 | |
| SCHEMBL8471904 | 0.75 | POLB (0.48) | ALDH1A1LMNAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL9282506 | 0.75 | KLK7 (0.59) | ALDH1A1LMNAHTTSMN1; SMN2TSHR | |
| SCHEMBL7663551 | 0.74 | ALDH1A1 (0.44) | ALDH1A1LMNAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL8472289 | 0.74 | ALDH1A1 (0.48) | ALDH1A1HTTKMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994396-A | Furansulfonic acid derivatives and pharmaceutical compositions containing the same | CENTAUR PHARMACEUTICALS, INC. (US) | 1999-11-30 | — | — | US | disclosed |