SCHEMBL8475560

SCHEMBL8475560

CC(C)(C)OC(=O)N1CCC(COC2CCC(c3ccc(OCc4ccccc4)cc3)CC2)CC1

nearest known ligand 0.67

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 10/20 0.67
YAP1 P46937 3/20 0.56
PRMT5 O14744 4/20 0.53
STS P08842 1/20 0.48
HCRTR2 O43614 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8475556 1.00 GPR119 (0.67) GPR119YAP1PRMT5STSHCRTR2
SCHEMBL22193619 0.88 PRMT5 (0.61) GPR119YAP1PRMT5STS
SCHEMBL7365948 0.87 YAP1 (0.56) GPR119YAP1PRMT5STS
SCHEMBL12813454 0.86 YAP1 (0.66) GPR119YAP1PRMT5STS
SCHEMBL8473896 0.85 GPR119 (0.79) GPR119HCRTR2
SCHEMBL7362766 0.85 GPR119 (0.79) GPR119HCRTR2
SCHEMBL8473888 0.84 GPR119 (0.68) GPR119HCRTR2
SCHEMBL8473886 0.84 GPR119 (0.68) GPR119HCRTR2
SCHEMBL21996804 0.82 GPR119 (0.57) GPR119YAP1STS
SCHEMBL12526668 0.82 GPR119 (0.57) GPR119YAP1STS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5994356-A ANTICOAGULANT KARL THOMAE (DE) 1999-11-30 US disclosed