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Sugi Predict / Compounds / SCHEMBL7365948

SCHEMBL7365948

SCHEMBL7365948

CC(C)(C)OC(=O)N1CCC(COC2CCN(c3ccc(OCc4ccccc4)cc3)CC2)CC1

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ YAP1 P46937 3/20 0.56
▸ GPR119 Q8TDV5 11/20 0.55
▸ PRMT5 O14744 4/20 0.53
▸ STS P08842 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8475560 0.87 GPR119 (0.67) YAP1GPR119PRMT5STS
SCHEMBL8475556 0.87 GPR119 (0.67) YAP1GPR119PRMT5STS
SCHEMBL12813454 0.86 YAP1 (0.66) YAP1GPR119PRMT5STS
SCHEMBL7363874 0.85 GPR119 (0.58) GPR119
SCHEMBL21996804 0.84 GPR119 (0.57) YAP1GPR119STS
SCHEMBL12526668 0.84 GPR119 (0.57) YAP1GPR119STS
SCHEMBL7364852 0.84 GPR119 (0.51) GPR119
SCHEMBL2883449 0.84 GPR119 (0.58) YAP1GPR119PRMT5
SCHEMBL31753740 0.82 GPR119 (0.59) GPR119
SCHEMBL76105 0.82 YAP1 (0.60) YAP1GPR119PRMT5STS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5994356-A ANTICOAGULANT KARL THOMAE (DE) 1999-11-30 — — US disclosed
EP-0892783-A1 CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION Dr. Karl Thomae GmbH (DE) 1999-01-27 — — EP disclosed
WO-1997037975-A1 CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION DR. KARL THOMAE GMBH (DE) 1997-10-16 — — WO disclosed