Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 9/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | KLRK1 | P26718 | 2/20 | 0.38 |
| ▸ | MICA | Q29983 | 2/20 | 0.38 |
| ▸ | RAET1L | Q5VY80 | 2/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474716 | 0.86 | ABCB1 (0.47) | MTTPESR1ESR2LIPEL3MBTL1 | |
| SCHEMBL8470465 | 0.85 | POLB (0.41) | MTTPESR1ESR2LIPEL3MBTL1 | |
| SCHEMBL8470892 | 0.85 | ABCB1 (0.42) | MTTPESR1ESR2LIPEL3MBTL1 | |
| SCHEMBL8582518 | 0.84 | ESR1 (0.44) | MTTPESR1ESR2LIPEL3MBTL1 | |
| SCHEMBL8472958 | 0.84 | SMO (0.43) | ESR1ESR2LIPEL3MBTL1KDM4E | |
| SCHEMBL6975568 | 0.84 | MTTP (0.51) | MTTPKDM4EALDH1A1LMNA | |
| SCHEMBL8473577 | 0.84 | HPGD (0.42) | MTTPESR1ESR2LIPEL3MBTL1 | |
| SCHEMBL8471797 | 0.84 | ESR1 (0.43) | MTTPESR1ESR2KLRK1MICA | |
| SCHEMBL8472959 | 0.83 | ABCB1 (0.39) | MTTPESR1ESR2LIPEL3MBTL1 | |
| SCHEMBL8473453 | 0.83 | ALDH1A1 (0.41) | MTTPESR1ESR2KLRK1MICA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919795-A | ATHEROSCLEROSIS THERAPY | PFIZER INC. (US) | 1999-07-06 | — | — | US | disclosed |