Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | MTTP | P55157 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | BRS3 | P32247 | 2/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474716 | 0.92 | ABCB1 (0.47) | ABCB1ABCC1ESR1ESR2MTTP | |
| SCHEMBL8472959 | 0.87 | ABCB1 (0.39) | ABCB1ABCC1ESR1ESR2MTTP | |
| SCHEMBL8470465 | 0.85 | POLB (0.41) | ABCB1ABCC1ESR1ESR2MTTP | |
| SCHEMBL8472074 | 0.85 | CHRNB2 (0.45) | ESR1ESR2MTTPALDH1A1 | |
| SCHEMBL8582518 | 0.85 | ESR1 (0.44) | ESR1ESR2MTTPKMT2AALDH1A1 | |
| SCHEMBL8472958 | 0.85 | SMO (0.43) | ESR1ESR2RAB9AKDM4ELMNA | |
| SCHEMBL8475640 | 0.85 | MTTP (0.39) | ABCB1ABCC1ESR1ESR2MTTP | |
| SCHEMBL8471797 | 0.84 | ESR1 (0.43) | ESR1ESR2MTTPKMT2AALDH1A1 | |
| SCHEMBL8473577 | 0.84 | HPGD (0.42) | ESR1ESR2MTTPRAB9AALDH1A1 | |
| SCHEMBL8471317 | 0.84 | ALDH1A1 (0.48) | ESR1ESR2MTTPALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919795-A | ATHEROSCLEROSIS THERAPY | PFIZER INC. (US) | 1999-07-06 | — | — | US | disclosed |