Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 10/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 10/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
| ▸ | ALPI | P09923 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476120 | 0.81 | ABCC8 (0.40) | ABCC8KCNJ11 | |
| SCHEMBL8473093 | 0.78 | ABCC8 (0.44) | ABCC8KCNJ11 | |
| SCHEMBL8716298 | 0.73 | MMP3 (0.31) | UTS2R | |
| SCHEMBL8476298 | 0.72 | ABCC8 (0.39) | ABCC8KCNJ11 | |
| SCHEMBL7079077 | 0.72 | ABCC8 (0.43) | ABCC8KCNJ11UTS2RGPR84 | |
| SCHEMBL8477302 | 0.71 | HCAR3 (0.31) | UTS2R | |
| SCHEMBL7593117 | 0.69 | ABCC8 (0.42) | ABCC8KCNJ11GPR84 | |
| SCHEMBL7080805 | 0.68 | ABCC8 (0.41) | ABCC8KCNJ11GPR84 | |
| SCHEMBL7074970 | 0.68 | ABCC8 (0.41) | ABCC8KCNJ11GPR84 | |
| SCHEMBL6802723 | 0.68 | ABCC8 (0.41) | ABCC8KCNJ11GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889002-A | CENTRAL NERVOUS SYSTEM DISORDERS; CARDIOVASCULAR DISORDERS; RESPIRATORY SYSTEM DISORDERS; GASTROINTESTINAL DISORDERS; ENDOCRINAL DISEASES | NOVO NORDISK A/S (DK) | 1999-03-30 | — | — | US | disclosed |