Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472179 | 0.98 | KDM4E (0.48) | KDM4ELMNASMN1; SMN2TP53ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8474181 | 0.94 | KDM4E (0.52) | KDM4ELMNASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL8472493 | 0.90 | KDM4E (0.52) | KDM4ELMNASMN1; SMN2TP53ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8476318 | 0.90 | KDM4E (0.50) | KDM4ELMNASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL8472860 | 0.87 | HTR7 (0.43) | KDM4ELMNAALDH1A1CNR2HTR7 | |
| SCHEMBL8475956 | 0.87 | KDM4E (0.54) | KDM4ELMNAALDH1A1MAPTHSD17B10 | |
| SCHEMBL8477351 | 0.87 | HRH3 (0.48) | KDM4ELMNASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL8472213 | 0.86 | KDM4E (0.53) | KDM4ELMNASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL8472293 | 0.85 | POLB (0.41) | KDM4EMAPTCNR2MEN1KMT2A | |
| SCHEMBL8472528 | 0.85 | KDM4E (0.49) | KDM4ELMNASMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |