Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 8/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898545 | 0.98 | CNR2 (0.44) | HTR7CNR2POLBTDP1KDM4E | |
| SCHEMBL8473694 | 0.95 | KDM4E (0.44) | CNR2KDM4EALDH1A1HTTNPC1 | |
| SCHEMBL8477346 | 0.94 | KDM4E (0.45) | CNR2KDM4EALDH1A1HTTNPC1 | |
| Hydrochloric Acid SCHEMBL8472609 | 0.89 | KDM4E (0.43) | CNR2POLBKDM4EALDH1A1HTT | |
| SCHEMBL8475143 | 0.88 | CNR2 (0.51) | CNR2ALDH1A1 | |
| SCHEMBL8475739 | 0.87 | KDM4E (0.48) | HTR7CNR2TDP1KDM4EALDH1A1 | |
| SCHEMBL8477333 | 0.87 | HTR7 (0.48) | HTR7CNR2POLBKDM4E | |
| Hydrochloric Acid SCHEMBL8473198 | 0.87 | KDM4E (0.46) | CNR2KDM4EALDH1A1HTTNPC1 | |
| SCHEMBL8473412 | 0.87 | LTA4H (0.51) | KDM4EALDH1A1HTTLMNA | |
| Hydrochloric Acid SCHEMBL8477245 | 0.86 | KDM4E (0.45) | CNR2KDM4EALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |