Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8479146 | 0.92 | HTT (0.45) | HRH3LTA4HKDM4ELMNAHTT | |
| Hydrochloric Acid SCHEMBL8474181 | 0.90 | KDM4E (0.52) | KDM4ELMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8473412 | 0.90 | LTA4H (0.51) | HRH3LTA4HKDM4ELMNAHTT | |
| Hydrochloric Acid SCHEMBL8476318 | 0.88 | KDM4E (0.50) | KDM4ELMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8472179 | 0.87 | KDM4E (0.48) | KDM4ELMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8475739 | 0.87 | KDM4E (0.48) | KDM4ELMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8477094 | 0.86 | LTA4H (0.58) | HRH3LTA4HKDM4ELMNAHTT | |
| SCHEMBL8475772 | 0.86 | SMN1; SMN2 (0.46) | HRH3LTA4HKDM4ELMNAALDH1A1 | |
| SCHEMBL8472271 | 0.86 | HRH3 (0.47) | HRH3LTA4HKDM4ELMNAHTT | |
| SCHEMBL8471934 | 0.86 | EPHX2 (0.48) | HRH3LTA4HKDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |