Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | DVL1 | O14640 | 1/20 | 0.40 |
| ▸ | DVL3 | Q92997 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8473304 | 1.00 | KDM4E (0.46) | KDM4ESMN1; SMN2RAB9ANPC1GAA | |
| Hydrochloric Acid SCHEMBL8474427 | 0.99 | KDM4E (0.46) | KDM4ESMN1; SMN2RAB9ANPC1GAA | |
| Hydrochloric Acid SCHEMBL8472265 | 0.98 | KDM4E (0.44) | KDM4ESMN1; SMN2RAB9ANPC1GAA | |
| Hydrochloric Acid SCHEMBL8472403 | 0.96 | KDM4E (0.42) | KDM4ESMN1; SMN2RAB9ANPC1GAA | |
| Hydrochloric Acid SCHEMBL8472257 | 0.95 | KDM4E (0.42) | KDM4ESMN1; SMN2RAB9ANPC1GAA | |
| SCHEMBL8472267 | 0.94 | KDM4E (0.45) | KDM4ESMN1; SMN2RAB9ANPC1GAA | |
| Hydrochloric Acid SCHEMBL8479395 | 0.94 | ALDH1A1 (0.40) | KDM4ESMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL8476064 | 0.94 | KDM4E (0.44) | KDM4ESMN1; SMN2RAB9ANPC1GAA | |
| Hydrochloric Acid SCHEMBL8477102 | 0.91 | SMN1; SMN2 (0.40) | KDM4ESMN1; SMN2RAB9ANPC1GAA | |
| SCHEMBL8474347 | 0.90 | RAB9A (0.41) | KDM4ESMN1; SMN2RAB9ANPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |