Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472347 | 0.91 | SMN1; SMN2 (0.41) | RCE1KDM4ESMN1; SMN2KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL8474668 | 0.91 | KDM4E (0.42) | RCE1KDM4ESMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL8477355 | 0.87 | GPR88 (0.38) | ALDH1A1LMNATSHR | |
| SCHEMBL8473415 | 0.84 | GPR88 (0.41) | ALDH1A1LMNATSHR | |
| SCHEMBL8472274 | 0.82 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1HPGDLMNARAB9A | |
| SCHEMBL8477091 | 0.81 | GPR88 (0.39) | ALDH1A1HSD17B10HPGDMAPK1LMNA | |
| SCHEMBL8472210 | 0.80 | KDM4E (0.43) | KDM4ESMN1; SMN2ALDH1A1HSD17B10HPGD | |
| SCHEMBL8471936 | 0.79 | GPR88 (0.36) | — | |
| SCHEMBL8474565 | 0.79 | SLC6A3 (0.42) | SMN1; SMN2ALDH1A1LMNATSHR | |
| SCHEMBL8475953 | 0.79 | KDM4E (0.44) | KDM4EKMT2AALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |