Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472210 | 0.88 | KDM4E (0.43) | KDM4ELMNATSHRALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL8474176 | 0.88 | SLC6A3 (0.39) | LMNATSHRALDH1A1TDP1SLC6A3 | |
| SCHEMBL8476838 | 0.85 | KDM4E (0.40) | KDM4ELMNATSHRALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL8476312 | 0.85 | SLC6A3 (0.36) | LMNATSHRALDH1A1TDP1SLC6A3 | |
| SCHEMBL8473691 | 0.84 | SLC6A3 (0.43) | LMNATSHRALDH1A1TDP1SLC6A3 | |
| SCHEMBL8472588 | 0.83 | ALDH1A1 (0.43) | KDM4ELMNATSHRMEN1ALDH1A1 | |
| SCHEMBL8472627 | 0.82 | SLC6A3 (0.43) | LMNATSHRALDH1A1TDP1SLC6A3 | |
| SCHEMBL8477355 | 0.82 | GPR88 (0.38) | LMNATSHRALDH1A1TDP1SLC6A3 | |
| SCHEMBL8475954 | 0.82 | KDM4E (0.45) | KDM4ELMNAMAPTTSHRMEN1 | |
| SCHEMBL8474450 | 0.81 | LMNA (0.47) | KDM4ELMNAMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |