Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476161 | 0.83 | ADRA1B (0.37) | ADRA1BHPGDKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL8472492 | 0.79 | SLC6A3 (0.35) | ALDH1A1SLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL8473142 | 0.79 | SLC6A3 (0.35) | ALDH1A1SLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL8472218 | 0.79 | ADRA1B (0.41) | ADRA1BHPGDKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL8472623 | 0.78 | ADRA1B (0.42) | ADRA1BHPGDKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL8476163 | 0.78 | ADRA1B (0.43) | ADRA1BHPGDKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL8472553 | 0.72 | ADRA1B (0.41) | ADRA1BHPGDKDM4EALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8473256 | 0.71 | L3MBTL1 (0.40) | ADRA1BHPGDKDM4EALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8474668 | 0.64 | KDM4E (0.42) | HPGDKDM4EALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL8472494 | 0.64 | KMT2A (0.36) | KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782987-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |