Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.58 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.58 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 3/20 | 0.55 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 4/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476000 | 0.81 | CARM1 (0.82) | SIGMAR1CARM1PRMT6MEN1TP53 | |
| SCHEMBL7463216 | 0.80 | MCHR1 (0.60) | SIGMAR1CARM1PRMT6MEN1TP53 | |
| Hydrochloric Acid SCHEMBL7259165 | 0.80 | SIGMAR1 (0.75) | SIGMAR1CARM1PRMT6MEN1TP53 | |
| SCHEMBL28442007 | 0.79 | SIGMAR1 (0.61) | SIGMAR1CARM1PRMT6MEN1TP53 | |
| Hydrochloric Acid SCHEMBL7469999 | 0.79 | MCHR1 (0.59) | SIGMAR1CARM1PRMT6MEN1TP53 | |
| SCHEMBL16273473 | 0.79 | SIGMAR1 (0.62) | SIGMAR1CARM1PRMT6MEN1TP53 | |
| SCHEMBL7382464 | 0.79 | SIGMAR1 (0.69) | SIGMAR1CARM1PRMT6MEN1TP53 | |
| SCHEMBL14587471 | 0.78 | ADRA1D (0.63) | SIGMAR1CARM1PRMT6MEN1TP53 | |
| SCHEMBL7950431 | 0.78 | ADH1B (0.53) | SIGMAR1CARM1PRMT6MEN1KMT2A | |
| SCHEMBL7382438 | 0.77 | SIGMAR1 (0.69) | SIGMAR1CARM1PRMT6MEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6001836-A | ANTAGONISTS OF NPY-INDUCED FEEDING BEHAVIOR | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-12-14 | — | — | US | disclosed |
| WO-1998054136-A1 | DIHYDROPYRIDINE NPY ANTAGONISTS: CYANOGUANIDINE DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-12-03 | — | — | WO | disclosed |