Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7520710 | 0.67 | DAO (0.31) | NAPRTDAOTSHRALDH1A1ALOX15 | |
| Bicarbonate SCHEMBL9350415 | 0.66 | P2RX4 (0.48) | NAPRTDAOTSHRALDH1A1ALOX15 | |
| SCHEMBL5058579 | 0.61 | GAA (0.35) | TSHRLMNA | |
| SCHEMBL29120205 | 0.60 | MAPT (0.45) | NAPRTDAOTSHRALDH1A1ALOX15 | |
| Phosphine SCHEMBL29120220 | 0.59 | — | — | |
| Phenol SCHEMBL28197260 | 0.59 | CA12 (0.69) | ALDH1A1ALOX15LMNA | |
| Acrylic Acid SCHEMBL11129651 | 0.57 | LMNA (0.50) | NAPRTDAOTSHRALDH1A1ALOX15 | |
| SCHEMBL9200523 | 0.57 | — | — | |
| SCHEMBL3767165 | 0.56 | MAPT (0.53) | TSHRALDH1A1ALOX15MAOAMAOB | |
| SCHEMBL33554 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1080723-C | Production of optically active benzothiepin salts | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-03-13 | — | — | CN | disclosed |
| US-5952512-A | Production of optically active benzothiepin salts | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| CN-1191538-A | Production of optically active benzothiepin salts | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-08-26 | — | — | CN | disclosed |
| EP-0842179-A1 | PRODUCTION OF OPTICALLY ACTIVE BENZOTHIEPIN SALTS | Takeda Chemical Industries, Ltd. (JP) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997003989-A1 | PRODUCTION OF OPTICALLY ACTIVE BENZOTHIEPIN SALTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-02-06 | — | — | WO | disclosed |