Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922049 | 0.84 | TSHR (0.33) | TSHRBCHE | |
| SCHEMBL10769983 | 0.73 | GPR84 (0.31) | GPR84 | |
| Acetic Acid SCHEMBL11657145 | 0.68 | NOX1 (0.33) | NAPRTBCHE | |
| SCHEMBL11167641 | 0.67 | ALDH1A1 (0.46) | NAPRTALDH1A1ALOX15 | |
| SCHEMBL8476375 | 0.67 | NAPRT (0.33) | DAOTSHRNAPRTALDH1A1ALOX15 | |
| SCHEMBL348197 | 0.62 | — | — | |
| SCHEMBL214797 | 0.62 | NOTUM (0.40) | DAOTSHRNAPRTALDH1A1ALOX15 | |
| SCHEMBL6542433 | 0.61 | DAO (0.31) | DAOTSHRNAPRTALDH1A1ALOX15 | |
| SCHEMBL563542 | 0.60 | KDM4E (0.35) | ALDH1A1ALOX15BCHEGPR84 | |
| Water SCHEMBL19744946 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1184381-A1 | PROCESSES FOR THE PREPARATION OF 2,3-DIHYDROTHIEPINE DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2002-03-06 | — | — | EP | disclosed |
| US-4242266-A | ANTIINFLAMMATORY AGENTS | CIBA-GEIGY CORPORATION (US) | 1980-12-30 | — | — | US | disclosed |