Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27506818 | 0.84 | — | — | |
| SCHEMBL7073682 | 0.81 | NT5E (0.30) | — | |
| SCHEMBL8476651 | 0.80 | NT5E (0.30) | — | |
| SCHEMBL7079890 | 0.76 | NT5E (0.30) | — | |
| SCHEMBL8719253 | 0.75 | HPGD (0.32) | — | |
| SCHEMBL7077929 | 0.70 | CXCR2 (0.31) | CXCR1CXCR2 | |
| SCHEMBL8476764 | 0.70 | — | — | |
| SCHEMBL7950990 | 0.70 | NT5E (0.42) | CYP2C9CXCR1CXCR2 | |
| SCHEMBL8473808 | 0.69 | — | — | |
| SCHEMBL2344068 | 0.68 | ABCC8 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1158290-C | Fused 1,2,4-thiadiazine and fused 1,4-thiazine derivatives, their preparation and use | ŵ��Ų�ڿ˹�˾ | 2004-07-21 | — | — | CN | disclosed |
| US-5889002-A | CENTRAL NERVOUS SYSTEM DISORDERS; CARDIOVASCULAR DISORDERS; RESPIRATORY SYSTEM DISORDERS; GASTROINTESTINAL DISORDERS; ENDOCRINAL DISEASES | NOVO NORDISK A/S (DK) | 1999-03-30 | — | — | US | disclosed |