SCHEMBL8719253

SCHEMBL8719253

CC(C)NC1=NSc2sc(Cl)c([N+](=O)[O-])c2N1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.32
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8719279 0.77
SCHEMBL8476909 0.75 CYP2C9 (0.31)
SCHEMBL7067299 0.74
SCHEMBL8580280 0.70 HPGD (0.39) HPGD
SCHEMBL8719182 0.69
SCHEMBL7071959 0.68
SCHEMBL8715747 0.67
SCHEMBL8720954 0.65 GAA (0.31)
SCHEMBL7004764 0.64 ABCC8 (0.31)
SCHEMBL7069173 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0876379-A1 FUSED 1,2,4-THIADIAZINE AND FUSED 1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1998-11-11 EP disclosed
WO-1997026265-A1 FUSED 1,2,4-THIADIAZINE AND FUSED 1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1997-07-24 WO disclosed