Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | FABP3 | P05413 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27853749 | 0.86 | ALDH1A1 (0.50) | ALDH1A1FEN1DPP4PBRM1TSHR | |
| SCHEMBL4504893 | 0.84 | ALDH1A1 (0.48) | ALDH1A1FEN1DPP4PBRM1TSHR | |
| SCHEMBL3006057 | 0.84 | ALDH1A1 (0.48) | ALDH1A1FEN1DPP4PBRM1TSHR | |
| SCHEMBL2866815 | 0.82 | ALDH1A1 (0.47) | ALDH1A1FEN1DPP4PBRM1TSHR | |
| SCHEMBL2336044 | 0.82 | AKR1B1 (0.62) | ALDH1A1FEN1AKR1B1FABP4AKR1B10 | |
| SCHEMBL1815662 | 0.82 | PNMT (0.55) | ALDH1A1FEN1DPP4PBRM1TSHR | |
| Hydrochloric Acid SCHEMBL6095750 | 0.81 | PNMT (0.53) | ALDH1A1FEN1DPP4PBRM1TSHR | |
| SCHEMBL80183 | 0.80 | ALDH1A1 (0.64) | ALDH1A1FEN1DPP4PBRM1TSHR | |
| SCHEMBL5163919 | 0.79 | BID (0.51) | KDM4EHSD17B10 | |
| SCHEMBL4987306 | 0.79 | ALDH1A1 (0.49) | ALDH1A1FEN1DPP4PBRM1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856334-A | ANTAGONIST FOR EOSINOPHILS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-05 | — | — | US | disclosed |
| EP-0773219-A1 | IMIDAZOQUINOLINE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-14 | — | — | EP | disclosed |