Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD1 | Q15139 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | CDK9 | P50750 | 1/20 | 0.51 |
| ▸ | PRKACA | P17612 | 4/20 | 0.48 |
| ▸ | PRKACG | P22612 | 4/20 | 0.48 |
| ▸ | PRKACB | P22694 | 4/20 | 0.48 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.48 |
| ▸ | CDK4 | P11802 | 3/20 | 0.48 |
| ▸ | CCND1 | P24385 | 3/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.48 |
| ▸ | CDK2 | P24941 | 3/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 4/20 | 0.42 |
| ▸ | PRKCA | P17252 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477326 | 0.85 | GSK3B (0.40) | PRKD1TDP1CCNT1PIM1CDK9 | |
| SCHEMBL8477367 | 0.83 | PRKD1 (0.53) | PRKD1TDP1CCNT1PIM1CDK9 | |
| SCHEMBL8467101 | 0.82 | PRKD1 (0.53) | PRKD1TDP1CCNT1PIM1CDK9 | |
| SCHEMBL8074697 | 0.80 | PRKD1 (0.58) | PRKD1TDP1CCNT1PIM1CDK9 | |
| SCHEMBL8464380 | 0.78 | PRKD1 (0.61) | PRKD1TDP1CCNT1PIM1CDK9 | |
| SCHEMBL8128283 | 0.78 | PRKCA (0.61) | PRKD1TDP1PIM1PRKACAPRKACG | |
| SCHEMBL8466746 | 0.76 | MEN1 (0.48) | PRKD1TDP1CCNT1PIM1CDK9 | |
| SCHEMBL8477009 | 0.76 | CCNT1 (0.51) | PRKD1TDP1CCNT1PIM1CDK9 | |
| SCHEMBL8467187 | 0.76 | MEN1 (0.45) | PRKD1TDP1CCNT1PIM1CDK9 | |
| SCHEMBL8464191 | 0.76 | CCNT1 (0.52) | PRKD1TDP1CCNT1PIM1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945440-A | Indolocarbazole imides and the use thereof | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1999-08-31 | — | — | US | disclosed |