Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8193803 | 0.98 | SIGMAR1 (0.52) | IDO1MAOAMAOBNAAASIGMAR1 | |
| SCHEMBL6964735 | 0.93 | IDO1 (0.61) | IDO1MAOAMAOBSIGMAR1FFAR1 | |
| SCHEMBL538854 | 0.83 | CA1 (0.48) | IDO1MAOAMAOBFFAR1TDP1 | |
| SCHEMBL198056 | 0.81 | IDO1 (0.58) | IDO1MAOAMAOBSIGMAR1L3MBTL1 | |
| SCHEMBL451456 | 0.80 | MAOA (0.74) | IDO1MAOAMAOBSIGMAR1L3MBTL1 | |
| SCHEMBL7449325 | 0.79 | TDP1 (0.61) | IDO1MAOAMAOBNAAASIGMAR1 | |
| SCHEMBL7448881 | 0.79 | TDP1 (0.61) | IDO1MAOAMAOBNAAASIGMAR1 | |
| SCHEMBL11516805 | 0.79 | SIGMAR1 (0.56) | IDO1MAOAMAOBNAAASIGMAR1 | |
| SCHEMBL7449055 | 0.79 | TDP1 (0.61) | IDO1MAOAMAOBNAAASIGMAR1 | |
| SCHEMBL8048487 | 0.79 | TDP1 (0.61) | IDO1MAOAMAOBNAAASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856334-A | ANTAGONIST FOR EOSINOPHILS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-05 | — | — | US | disclosed |
| EP-0773219-A1 | IMIDAZOQUINOLINE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-14 | — | — | EP | disclosed |
| EP-0456112-B1 | Cyclohexenone oxime ethers, process for their preparation and their use as herbicides | BASF AG (DE) | 1994-08-31 | — | — | EP | disclosed |