Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | GRK6 | P43250 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8479043 | 0.88 | MAPK1 (0.37) | PTGS2PTGS1FFAR1KDM4EMAPT | |
| SCHEMBL8583197 | 0.84 | PTGS2 (0.35) | PTGS2PTGS1FFAR1S1PR1KDM4E | |
| SCHEMBL8582978 | 0.84 | PTGS2 (0.35) | PTGS2PTGS1FFAR1S1PR1KDM4E | |
| SCHEMBL8476204 | 0.81 | PTGS2 (0.34) | PTGS2PTGS1FFAR1S1PR1KDM4E | |
| SCHEMBL8477185 | 0.79 | KDM4E (0.38) | PTGS2PTGS1FFAR1KDM4EMAPT | |
| SCHEMBL8478886 | 0.79 | KCNH2 (0.34) | PTGS2PTGS1S1PR1 | |
| SCHEMBL8480091 | 0.79 | PTGS2 (0.47) | PTGS2LMNA | |
| SCHEMBL8477928 | 0.79 | PTGS2 (0.38) | PTGS2PTGS1FFAR1S1PR1KDM4E | |
| SCHEMBL8480653 | 0.78 | SLC10A2 (0.39) | PTGS2PTGS1FFAR1KDM4EMAPT | |
| SCHEMBL8479336 | 0.75 | GCGR (0.31) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |