SCHEMBL8480653

SCHEMBL8480653

CCc1[c]c(-c2ccc(OC)c(C)c2)c(C)c(-c2ccc(OC)c(C)c2)c1OC

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC10A2 Q12908 2/20 0.39
KDM4E B2RXH2 2/20 0.34
MAPT P10636 1/20 0.34
PDGFRB P09619 1/20 0.34
PDGFRA P16234 1/20 0.34
PTGS2 P35354 5/20 0.34
HTT P42858 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
PTGS1 P23219 2/20 0.33
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
HPGD P15428 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33
FFAR1 O14842 1/20 0.32
GRK6 P43250 1/20 0.31
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8474433 0.85 MGAM (0.39) SLC10A2
SCHEMBL8478485 0.82 MGAM (0.36) SLC10A2KDM4EMAPTPDGFRBPDGFRA
SCHEMBL8479043 0.82 MAPK1 (0.37) SLC10A2KDM4EMAPTPDGFRBPDGFRA
SCHEMBL8581095 0.81 MAPK1 (0.36) SLC10A2KDM4EMAPTPDGFRBPDGFRA
SCHEMBL8474699 0.80 MAPT (0.37) SLC10A2KDM4EMAPTHPGDKMT2A
SCHEMBL8478465 0.80 KDM4E (0.35) SLC10A2KDM4EMAPTPDGFRBPDGFRA
SCHEMBL8581223 0.78 MAPK1 (0.36) SLC10A2KDM4EMAPTPDGFRBPDGFRA
SCHEMBL8477376 0.78 PTGS2 (0.36) KDM4EMAPTPDGFRBPDGFRAPTGS2
SCHEMBL8480669 0.78 HEXA (0.38) PTGS2
SCHEMBL8477185 0.77 KDM4E (0.38) KDM4EMAPTPDGFRBPDGFRAPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6004988-A Carboxylic acid derivatives, their preparation and their use BASF AKTIENGESELLSCHAFT (DE) 1999-12-21 US disclosed